New Breeding Breakthrough of Grouper, a New NCKU’s Research
成大生科研究新突破,為石斑魚養殖打造新福音
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        Professor Hong Jianrui, a successful undergraduate researcher in molecular virology, said that because the Grouper iridescent virus (GIV) and necrosis virus (NNV) had huge relationship to Taiwan's current aquaculture and breeding workers. The virus had caused 80% of the industry lost with the impact toward more than 20 fish species in Taiwan. 

        Therefore, the research team found that with the newly developed combined functional addition, we can effectively reduce virus reproduction by inhibiting autophagy and reduce the virus toxicity by more than 100 times. Also, it can effectively improve cell survival and increase the breeding rate of 30 - 50% of the fish. With the new discovery of the research, the team’s report stated that cranial nerve necrosis virus infection triggers superoxide and MTOR-mediated signaling pathways and initiates autophagy in an early-mid viral replication phase. 

        台灣石斑不只養殖技術好,產值也很高,擁有「石斑王國」之稱,而近幾年國內石斑魚一直深受石斑虹彩病毒(GIV)及神經壞死病毒(NNV),損失高達 8 成,成功大學生科產業系洪健睿教授近期將發表研究成果指出,新研發出的組合式機能性添加物,透過抑制細胞自噬作用能有效降低病毒繁殖,及降低病毒毒性百倍以上,有效提高細胞存活及增加魚隻三至五成育成率。

        石斑魚經濟價值高,但一旦魚苗感染神經壞死病毒,死亡率高達6至8成,國立成功大學生物科學研究所教授洪健睿率領團隊,經過7、8年的研究,研發出可抗神經壞死病毒的機能性飼料添加物,魚苗只要吃了混合小分子RNA載體的飼料後,就能阻斷病毒複製基因,1吋以下的魚苗存活率,將可由4成提高至8成以上,該項技術已於去年取得台灣專利。

        石斑魚經濟價值高,但一旦魚苗感染神經壞死病毒,死亡率高達6至8成,國立成功大學生物科學研究所教授洪健睿率領團隊,經過7、8年的研究,研發出可抗神經壞死病毒的機能性飼料添加物,魚苗只要吃了混合小分子RNA載體的飼料後,就能阻斷病毒複製基因,1吋以下的魚苗存活率,將可由4成提高至8成以上,該項技術已於去年取得台灣專利。